Xylometazoline Addiction Rehab: Symptoms and Treatment
Life changing care by the best therapist team in the world, in the most beautiful location you can wish for
Xylometazoline is a medically active substance used for relieving nasal congestion. According to research by Eccles, R., Eriksson, M., Garreffa, S., & Chen, S. (2008), xylometazoline is an effective and well-tolerated decongestant that significantly alleviates nasal congestion. It offers long-lasting relief with just one spray, allowing patients to breathe more easily for longer. It works by narrowing blood vessels in the nose, reducing swelling and congestion.
The addictive nature of xylometazoline is linked to the relief it provides. With prolonged use, the body can become dependent on the substance for nasal relief, leading to a constant need for the medication.
Substances similar to xylometazoline include oxymetazoline and naphazoline. These active ingredients have a similar effect on the body and can have the same addictive properties.
In the short term, xylometazoline relieves nasal congestion, but it can also cause side effects such as increased heart rate, insomnia, and anxiety. With frequent use, these effects can worsen.
Although xylometazoline is effective, long-term use can be harmful. It can lead to chronic nasal congestion, a condition known as rhinitis medicamentosa.
If you want to stop using xylometazoline, the two main steps are reducing the dosage and seeking medical help. Support from a healthcare provider is crucial for success.
When quitting xylometazoline, withdrawal symptoms may occur, including extreme nasal congestion and anxiety. These symptoms can last for a week or longer.
Is Xylometazoline Dangerous?
Although xylometazoline is generally considered safe, it can be dangerous if used incorrectly. Excessive use can lead to rebound congestion, where the nasal passages remain blocked after seven days. Additionally, long-term use can damage the nasal mucosa.
Importantly, xylometazoline is not considered safe for children younger than three months. In children, excessive use can damage the central nervous system, in extreme cases even leading to coma. It can also interact with certain medications, like MAO inhibitors, leading to medical problems. Therefore, it’s crucial to always consult a doctor before using this medication.
According to a study by Ahmed and Menshawy (2021) in the Journal of Pharmaceutical Research, xylometazoline is often prescribed in outpatient clinics. However, it can cause various side effects, so its prescription needs continuous assessment to prevent these side effects and reduce interactions with other medications.
What Signs Indicate Xylometazoline Addiction?
Several signs indicate possible xylometazoline addiction.
- Frequent use: Using the nasal spray more often than prescribed.
- Inability to breathe: Feeling constant suffocation without the spray.
- Lack of sleep: Unable to sleep without using the nasal spray.
- Anxiety: Experiencing anxiety about leaving home without a bottle.
- Palpitations: Experiencing heart palpitations after use.
- Recurring hallucinations: In extreme cases, experiencing hallucinations.
- Slowed heartbeat: Excessive use can lead to a slow, irregular heartbeat.
- Worsening congestion: Congestion worsens after a week of use.
- Inability to stop: Unable to stop using, even for a few days.

How to Quit a Xylometazoline Addiction?
Quitting a xylometazoline addiction requires a detailed plan. The first step is deciding to quit. This is the biggest challenge but is necessary for success.
The duration of withdrawal symptoms varies, but they decrease after a few weeks. Patients who are addicted often experience a blocked nose during withdrawal. To alleviate this issue, you can dilute decongestant nasal sprays. This helps lower the active ingredients and relieve the nose.
An alternative method is using a saline solution. This can be applied indefinitely and helps clean the nose and soothe the mucous membranes. It is also helpful to massage the nostrils. This stimulates natural secretions and helps unblock the nose.
When quitting, it is also important to support the nose. This can be done using a PEP device, which supports breathing and helps clean the nose. Physical training can also help regulate breathing.
What Happens During the Treatment of Xylometazoline Addiction in a Rehab Clinic?
In a rehab clinic, xylometazoline addiction is treated professionally. The treatment includes multiple facets, including therapy and breathing exercises. The therapy is aimed at regenerating the nasal mucosa, chronically affected by the repeated effects of xylometazoline. Additionally, bronchial hypersensitivity is reduced through inhalation of a saline solution.
There are rehab clinics in the US, UK and abroad that treat xylometazoline addiction. These clinics use a device known as an OPEP (Oscillating Positive Expiratory Pressure) device, to open the airways and loosen the mucus. The device produces vibrations transmitted through the nose and throat, having an expectorant effect.
The OPEP device increases exhalation pressure, resulting in increased airflow and reduced gas buildup. This improves ventilation and reduces the diameter of the airways. The device also generates vibrations that help loosen mucus and remove excess mucus from the nose.
Studies have shown that this treatment significantly improves nasal mucosa drainage. Moreover, the treatment reduces bronchial hypersensitivity.
What Are the Withdrawal Symptoms of Xylometazoline?
The most common withdrawal symptoms of xylometazoline are discomfort and challenges when quitting. It can lead to severe nasal congestion, a blocked nose, runny nose, sore throat, sneezing, breathing difficulties, headache, sinus pressure, anxiety, restlessness, sleep problems, nausea, dizziness, dryness, and irritation in the nasal passages, and a burning or stinging feeling. The severity and duration of these symptoms can vary depending on the frequency of xylometazoline use.
It is important to know how to manage these symptoms. Increasing fluid intake can help relieve dryness and irritation in the nasal passages. Rest and relaxation can help manage anxiety and restlessness. If symptoms are severe or persistent, it is advisable to consult a doctor or addiction specialist. Professional help can increase the chances of successfully quitting.
It is important to note that the withdrawal symptoms of xylometazoline can differ from those of other nasal sprays. This depends on the specific ingredients and how your body reacts to them.
How Does Xylometazoline Addiction Differ from Other Drugs?
Xylometazoline addiction differs from other drugs in several ways. Unlike harder drugs, such as cocaine, xylometazoline is not necessarily considered a strong addiction. It’s a nasal spray often used for temporary relief of nasal congestion. It is available over the counter (OTC) and popular among people suffering from chronic sinus and throat problems.
However, according to medical professionals, using xylometazoline can lead to a vicious cycle. It provides temporary relief but also causes congestion, leading people to keep using it.
Another difference is that xylometazoline, unlike quitting other drugs, does not directly give a ‘high.’ It works on the inside of the nose and extends its function. But with prolonged use, it can cause changes in the brain, similar to those seen with other drug abuse.